934321

L-Valyl-L-citrulline

≥95%

• 동의어(들): L-Valyl-N⁵-(aminocarbonyl)-L-ornithine, Val-Cit
• 실험식(Hill 표기법): C₁₁H₂₂N₄O₄
• CAS Number: 159858-33-0
• Molecular Weight: 274.32
• UNSPSC 코드: 12352209
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥95%
• 형태: powder or crystals
• 색상: off-white to light yellow
• 저장 온도: 2-8°C

설명

애플리케이션

This is a cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC & Bioconjugation).

특징 및 장점

Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. The Boc group can be deprotected under acidic conditions to generate a free amine group. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable