927295

Linear polyethylenimine-block-poly(ethylene glycol)

PEG average M_n 2,000, PEI average M_n 10,000

• 동의어(들): PEG-b-PEI, PEG-PEI, Poly(ethylene glycol)-block-polyethylenimine
• Linear Formula: CH₃(C₂H₄O)_n(C₂H₅N)_mOH
• UNSPSC 코드: 12162002
• NACRES: NA.25

속성

• 형태: powder or solid
• Quality Level: 100
• 분자량: PEG M_n 2,000 Da; PEG average M_n 2,000; PEI M_n 10,000 Da; PEI average M_n 10,000
• 색상: white to pale yellow
• 저장 온도: 2-8°C

설명

애플리케이션

Due to their low immunogenicity profiles, polymeric nonviral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable