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Merck
모든 사진(1)

문서

916145

Sigma-Aldrich

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate)

natural origin, PHH content 4.1 %, PHV content 2.3 %

동의어(들):

PHB, PHBH, PHBV, Polyhydroxybutyrate

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About This Item

Linear Formula:
[C4H6O2]x[C5H8O2]y[C6H10O2]z
UNSPSC 코드:
12162002
NACRES:
NA.23

Quality Level

형태

powder

분자량

average Mn 1,000,000

구성

3-Hydroxyhexanoic acid content, 4.1%
3-Hydroxyvaleric acid content, 2.3%
PHH content, 4.1%
PHV content, 2.3%

색상

white to off-white

애플리케이션

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate) is a biocompatible and biodegradable polymer produced by fermentation of genetically modified microorganisms. Poly(3-hydroxybutyric acid) (PHB) is a common polyhydroxyalkanoate (PHA), it has been widely used for food packaging, medical implants, biodegradable sutures and drug delivery systems due to its biocompatible and biodegradable properties. PHB has been investigated as drug delivery micro- and nano-carriers.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Anupama Shrivastav et al.
BioMed research international, 2013, 581684-581684 (2013-08-29)
Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal
Sumeet Kapoor et al.
International journal of pharmaceutics, 511(2), 876-889 (2016-08-06)
Faster biodegradation, immunogenicity and lack of cell penetrative capabilities are hurdles in development of peptidyl drugs for cancer therapy. Polymeric carriers can be used to overcome these problems. The present study is focused on the use of polyhydroxybutyrate as a
K Juni et al.
Critical reviews in therapeutic drug carrier systems, 3(3), 209-232 (1987-01-01)
Poly(hydroxy acids) so far have been examined for use in drug delivery in limited number, while the advantageous use of the polymers has been recognized due to their biodegradability and biocompatibility. Homo- and copolymers of lactic acid and glycolic acid

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