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Merck
모든 사진(2)

주요 문서

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911445

Sigma-Aldrich

Polyester bis-MPA dendron, 4 Rhodamine, 1 carboxyl (core)

generation 2

동의어(들):

Bis-MPA dendron, Fluoresenct linker, Fluoresent dendron

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C127H142Cl4N8O18
Molecular Weight:
2210.34
UNSPSC 코드:
12162002
NACRES:
NA.23

양식

solid

분자량

generation 2

표면기 개수

4

색상

red to pink

작용기

carboxylic acid (core)

저장 온도

−20°C

관련 카테고리

일반 설명

  • Polymer architecture: Dendron
  • End Group Functionality: Rhodamine
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

애플리케이션

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allow their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers is biocompatible and biodegradable, making them suitable for biomedical applications.
The core of this product is functionalized by carboxyl groups, which can be readily used in bioconjugation. The rhodamine labeled corona allows for application in bioimaging.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Patrik Stenström et al.
Molecules (Basel, Switzerland), 23(8) (2018-08-17)
Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1⁻G4), modified to bear
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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