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일반 설명
DLAM-LVproS-13CH3 kit has 13CH3 Isotopomer precursors and contains protocol instructions for creation of isotopically-labeled proteins.
애플리케이션
For detection of long-range nOes or for the NMR study of large proteins
Methyl groups of leucine and valine is labeled with 13CH3 using DLAM-LVproS-13CH3 kit. This kit has been tested with protein isotopic labeling in E. coli. DLAM-LVproS-13CH3 is used in NMR spectroscopy to provide site-resolved information for intrinsically disordered protein or regions of proteins in NMR spectroscopic studies.
포장
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class Code
11 - Combustible Solids
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Stereospecific isotopic labeling of methyl groups for NMR spectroscopic studies of high-molecular-weight proteins.
Angewandte Chemie (International ed. in English), 49(11), 1958-1962 (2010-02-17)
Current opinion in structural biology, 32, 113-122 (2015-04-17)
Nuclear magnetic resonance (NMR) spectroscopy is a uniquely powerful tool for studying the structure, dynamics and interactions of biomolecules at atomic resolution. In the past 15 years, the development of new isotopic labeling strategies has opened the possibility of exploiting
Current opinion in structural biology, 35, 60-67 (2015-09-26)
Intermolecular interactions are indispensible for biological function. Here we discuss how novel NMR techniques can provide unique insights into the assembly, dynamics and regulation of biomolecular complexes. We focus on applications that exploit the methyl TROSY effect and show that
문서
Methyl groups are ideal probes for studying protein structure and function by NMR. Choose among user-friendly kits for isotope labeling of a single type or multiple types of methyl groups.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.