905186

(9-Bromononyl)triphenylphosphonium bromide

• 동의어(들): Bromononane TPP mitochondrial tag, Mitochondria-targeting probe building block, Phosphonium lipocation tag
• 실험식(Hill 표기법): C₂₇H₃₃Br₂P
• CAS Number: 90052-38-3
• Molecular Weight: 548.33
• UNSPSC 코드: 12352200

속성

• 양식: liquid
• 저장 온도: 2-8°C
• InChI: 1S/C27H33BrP.BrH/c28-23-15-4-2-1-3-5-16-24-29(25-17-9-6-10-18-25,26-19-11-7-12-20-26)27-21-13-8-14-22-27;/h6-14,17-22H,1-5,15-16,23-24H2;1H/q+1;/p-1
• InChI key: ACKJFSDDEOFXHT-UHFFFAOYSA-M

설명

애플리케이션

Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This bromononane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria.

기타 정보

Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion

Targeting lipophilic cations to mitochondria

Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable