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Merck
모든 사진(1)

Key Documents

901322

Sigma-Aldrich

Bis-MPA-NHBoc dendrimer

generation 4

동의어(들):

Bis-MPA dendrimer, NHBoc functionalized dendrimer, PFD-G4-TMP-NH-Boc

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About This Item

실험식(Hill 표기법):
C615H998N48O282
Molecular Weight:
13576.66
UNSPSC 코드:
12162002
NACRES:
NA.23

형태

solid

Quality Level

분자량

generation 4

표면기 개수

48

색상

white to off-white

저장 온도

−20°C

일반 설명

  • Polymer architecture: Dendrimer
  • Generation: 4
  • End group functionality: Boc-protected amine
  • No. surface groups: 48
  • Calculated mol. wt.: 13576.80 g/mol
  • Boc: tert-Butyloxycarbonyl
  • Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid.

애플리케이션

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrimers synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After boc deprotection, amine-functionalized dendrimers can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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