900913

Tetrazine-PEG5-NHS ester

≥95%

• 동의어(들): Tz-PEG5-NHS
• 실험식(Hill 표기법): C₂₇H₃₆N₆O₁₀
• CAS Number: 1682653-80-0
• Molecular Weight: 604.61
• MDL number: MFCD28505547
• UNSPSC 코드: 12352108
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 형태: powder or crystals
• 반응 적합성: reaction type: click chemistry; reagent type: linker
• 작용기: NHS ester
• 저장 온도: −20°C
• SMILES string: O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O

설명

일반 설명

Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

애플리케이션

Tetrazine-PEG5-NHS ester (Tz-PEG₅-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable