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Merck
모든 사진(1)

주요 문서

808350

Sigma-Aldrich

TokeOni

동의어(들):

2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid hydrochloride salt, AkaLumine-HCl, Soluble NIR emission luciferin

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About This Item

실험식(Hill 표기법):
C16H19ClN2O2S · xHCl
Molecular Weight:
338.85 (free base basis)
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.23

양식

powder

Quality Level

저장 온도

−20°C

SMILES string

CN(C)C1=CC=C(/C=C/C=C/C2=N[C@@H](C(O)=O)CS2)C=C1.[H]Cl

InChI

1S/C16H18N2O2S.ClH/c1-18(2)13-9-7-12(8-10-13)5-3-4-6-15-17-14(11-21-15)16(19)20;/h3-10,14H,11H2,1-2H3,(H,19,20);1H/b5-3+,6-4+;/t14-;/m1./s1

InChI key

PZCNKVAGZCXXHX-SSRSOBHISA-N

일반 설명

  • Luciferin is a generic term for the light-emitting compound found in organisms that generate bioluminescence.
  • TokeOni is a new NIR emission luciferin analogue having luminescence peak at 670 ~ 680 nm with a peak range in the near-infrared (NIR) region.
  • TokeOni has the enhanced solubility of >10 mg/mL compared to HCl free (0.2 mg/mL).

애플리케이션

  • Bioimaging.
  • in vivo imaging.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore.
Chihiro M, et al.
Tetrahedron, 69(46), 9726-9734 (2013)
Development of simple firefly luciferin analogs emitting blue, green, red and near-infrared biological window light.
Satoshi I, et al.
Tetrahedron, 69(19), 3847-3856 (2013)
Gi Bum Kim et al.
Cell, 179(1), 251-267 (2019-09-21)
In situ transgenesis methods such as viruses and electroporation can rapidly create somatic transgenic mice but lack control over copy number, zygosity, and locus specificity. Here we establish mosaic analysis by dual recombinase-mediated cassette exchange (MADR), which permits stable labeling

문서

Overall results suggest that seMpai is a suitable substrate of near-infrared BLI for many biological experiments. Its high solubility in neutral buffer conditions further extends the bioluminescent application of TokeOni derivatives.

Bioluminescence imaging (BLI) systems allows for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.

Synthesis and Applications of Graphene Nanoribbons Synthesized

관련 콘텐츠

Organic electronics utilizes organic conductors and semiconductors for applications in organic photovoltaics, organic light-emitting diodes, and organic field-effect transistors.

Global Trade Item Number

SKUGTIN
808350-100MG
808350-200MG4065269250159
808350-25MG4061833249963
808350-500MG4065269042525
808350-5MG4061832995380

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