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Merck
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주요 문서

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677418

Sigma-Aldrich

Hydroxyapatite

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

동의어(들):

Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate

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모든 사진(2)

About This Item

Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
12167-74-7
Molecular Weight:
502.31
EC Number:
235-330-6
MDL number:
MFCD00010904
UNSPSC 코드:
12352302
PubChem Substance ID:
24885371
NACRES:
NA.23
분석:
≥97%
양식:
nanopowder
solid

Quality Level

100

분석

≥97%

양식

nanopowder
solid

표면적

>9.4 m2/g

입자 크기

<200 nm (BET)

mp

1100 °C (lit.)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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일반 설명

Hydroxyapatite(HA) belongs to the family of Ca apatite which resembles natural bone in both structure and chemical composition. It can be prepared by various techniques such as chemical precipitation, hydrothermal, electrospinning, and self-propagating combustion. It is widely used as an implant material for bone regeneration, a drug carrier, and a gene delivery system due to its bioactive and biocompatible nature.

애플리케이션

Nanoscale hydroxyapatite particles can be used to prepare bone tissue engineering materials due to their slow biodegradability in situ, good osteoconductive and osteoinductive capabilities.

Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles can be used as a drug carrier for vancomycin. Hydroxyapatite nanoparticles control the release of antibiotics after the implantation of a scaffold in the body.

Porous hydroxyapatite microspheres exhibit a high adsorptive capacity for heavy metals and can be used for the treatment of heavy metal contaminated water.

특징 및 장점

  • Bioactive and biocompatible
  • Good mechanical strength
  • Porous structure
  • Osteoconductive and osteointegrative properties

법적 정보

Product of Engi-Mat Co.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

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시험 성적서(COA)

Lot/Batch Number
MKCQ2685
MKCN9004
MKCM1889
MKCK9555
MKCK8172

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Sang-Soo Kim et al.
Biomaterials, 27(8), 1399-1409 (2005-09-20)
Biodegradable polymer/bioceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. However, conventional methods for fabricating polymer/bioceramic composite scaffolds often use organic solvents (e.g., the solvent casting and particulate leaching (SC/PL)
Michiko Sato et al.
Biomaterials, 27(11), 2358-2369 (2005-12-13)
In order to improve orthopedic implant performance, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (HA) powders to coat titanium. HA was synthesized through a wet chemical process. The precipitated powders were either sintered at 1100
Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles.
Pang YX, et al.
J. Eur. Ceram. Soc., 23(10), 1697-1704 (2003)
Hydroxyapatite nanoparticles: a review of preparation methodologies
Ferraz MP, et al.
Journal of Applied Biomaterials & Biomechanics : JABB, 2(2), 74-80 (2004)
Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
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