콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

View All Documentation

560146

Sigma-Aldrich

4-Chloro-2-iodobenzoic acid

97%

로그인조직 및 계약 가격 보기
모든 사진(1)

About This Item

Linear Formula:
C6H3Cl(I)COOH
CAS Number:
13421-13-1
Molecular Weight:
282.46
MDL number:
MFCD00060676
UNSPSC 코드:
12352100
PubChem Substance ID:
24879847
NACRES:
NA.22

Quality Level

100

분석

97%

mp

163-167 °C (lit.)

작용기

carboxylic acid
chloro
iodo

SMILES string

OC(=O)c1ccc(Cl)cc1I

InChI

1S/C7H4ClIO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11)

InChI key

LRRDANNSUCQNDU-UHFFFAOYSA-N

관련 카테고리

일반 설명

4-Chloro-2-iodobenzoic acid is an electron-deficient substituted 2-iodobenzoic acid. It reacts with ynamide to provide the 3,4-disubstituted isocoumarin.

애플리케이션

4-Chloro-2-iodobenzoic acid may be used to synthesize:
  • 6-chloro-3-(4-methoxyphenyl)-1H-isochromen-1-one
  • (Z)-3-benzylidene-5-chloroisobenzofuran-1(3H)-one
  • 6-chloro-3-pentyl-1H-isochromen-1-one
  • 4-chloro-2-iodobenzophenone

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
MKCN0649
MKBV5755V
MKBT4604V
MKBL6916V
MKBG7925V

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Regioselective synthesis of 3, 4-disubstituted isocoumarins through the Pd-catalyzed annulation of 2-iodoaromatic acids with ynamides.
Liu H, et al.
Chemical Communications (Cambridge, England), 52(41), 6801-6804 (2016)
Veronika Hampl et al.
Scientia pharmaceutica, 79(1), 21-30 (2011-05-28)
New isocoumarins were prepared in an efficient way from 2-iodobenzoic acid derivatives and hept-1-yne in a Sonogashira reaction, followed by spontaneous cyclization. Catalytic hydrogenation gave the corresponding dihydroisocoumarins. A 4-chloroisocoumarin was prepared on an alternative pathway. Some of the new
The synthesis and electronic absorption spectra of 3-phenyl-3 (4-pyrrolidino-2-substituted phenyl)-3H-naphtho [2, 1-b] pyrans: further exploration of the ortho substituent effect.
Gabbutt CD, et al.
Tetrahedron, 62(4), 737-745 (2006)
Regioselective One-Pot Synthesis of Isocoumarins and Phthalides from 2-Iodobenzoic Acids and Alkynes by Temperature Control.
Kumar MR, et al.
Advanced Synthesis & Catalysis, 355(16), 3221-3230 (2013)

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.