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535311

Sigma-Aldrich

Poly(N-isopropylacrylamide)

Mn ~40,000

동의어(들):

NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM

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About This Item

Linear Formula:
CH3(C6H11NO)nCH3
CAS Number:
25189-55-3
MDL number:
MFCD00284282
UNSPSC 코드:
12162002
PubChem Substance ID:
24877546
NACRES:
NA.23

분자량

Mn 20,000-60,000
Mn ~40,000

Quality Level

100

mp

96 °C

SMILES string

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

InChI key

WDFKEEALECCKTJ-UHFFFAOYSA-N

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애플리케이션

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering
Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

물리적 형태

Thermosensitive polymer, hydrogel

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
MKCM8563
MKCM8561
MKCM4547
MKCL5014
MKCL5016

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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이미 열람한 고객

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1 of 1

N-Isopropylmethacrylamide 97%

Sigma-Aldrich

423548

N-Isopropylmethacrylamide

Manuel Pernia Leal et al.
ACS nano, 6(12), 10535-10545 (2012-11-03)
We report a procedure to grow thermo-responsive polymer shells at the surface of magnetic nanocarriers made of multiple iron oxide superparamagnetic nanoparticles embedded in poly(maleic anhydride-alt-1-ocatadecene) polymer nanobeads. Depending on the comonomers and on their relative composition, tunable phase transition
Albert J de Graaf et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 582-590 (2012-09-14)
In this paper it is shown that when a thermosensitive hydrogel based on poly(N-isopropylacrylamide)-poly(ethylene glycol)-poly(N-isopropylacrylamide) (pNIPAm-PEG-pNIPAm) was transferred into water, flower-like micelles were continuously released as long as the medium was regularly refreshed. On the other hand, if the medium
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The
Jinseok Byun et al.
Chemical communications (Cambridge, England), 48(74), 9278-9280 (2012-08-09)
We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
Pengju Pan et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14347-14356 (2012-09-28)
Linear and miktoarm star-shaped diblock copolymers consisting of single-stranded DNA and poly(N-isopropylacrylamide) (PNIPAAm) with various compositions were synthesized via atom transfer radical polymerization and click chemistry. The temperature-responsive phase transition behavior, micellization, was systematically examined using UV-vis spectrometry, high-sensitivity differential
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문서

Universal Platform for Surface Modification Employing Grafted Polymer Layers

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

Universal Platform for Surface Modification Employing Grafted Polymer Layers

Universal Platform for Surface Modification Employing Grafted Polymer Layers

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

Stimuli-Responsive Materials as Intelligent Drug Delivery Systems

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

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