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Merck
모든 사진(1)

문서

172472

Sigma-Aldrich

Isopropyl myristate

98%

동의어(들):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
Beilstein:
1781127
EC Number:
MDL number:
UNSPSC 코드:
12352100
eCl@ss:
39022421
PubChem Substance ID:
NACRES:
NA.22

분석

98%

형태

liquid

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

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일반 설명

IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.

애플리케이션

Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus (FK506) solvent.

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point (°F)

>302.0 °F

Flash Point (°C)

> 150 °C

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

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Naproxen (Np) is an example of a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of pain and inflammation. In order to develop an alternative formulation for the topical administration of Np, microemulsions were evaluated as delivery vehicles. Four
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International journal of pharmaceutics, 464(1-2), 19-26 (2014-01-25)
We developed an oil/water-type tacrolimus (FK506) cream formulation as an alternative to Protopic ointment for atopic dermatitis treatment. We determined the effects of solvents used in topical preparations on FK506 solubility and stability, and evaluated FK506 transdermal absorption into rat
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In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
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To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and

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