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Merck

RNASEH2A

ribonuclease H2, subunit A

동의어:
AGS4, JUNB, RNASEHI, RNHIA, RNHL
:
UniProtKB ID:
Clone ID:
  • Human(10535) Summary: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
  • Mouse(69724) ribonuclease H2, large subunit
  • Rat(364974) ribonuclease H2, subunit A
  • Zebrafish(393195) ribonuclease H2, subunit A
  • domestic cat(101086121) ribonuclease H2, subunit A
  • dog(484925) ribonuclease H2, subunit A
  • cow(512830) ribonuclease H2, subunit A
  • sheep(101105746) ribonuclease H2, subunit A
  • Goat(100860936) ribonuclease H2, subunit A
  • domestic guinea pig(100715505) ribonuclease H2, subunit A
  • naked mole-rat(101714999) ribonuclease H2, subunit A

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-RNASEH2A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-RNASEH2A antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-RNASEH2A antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
bovine, goat, horse, human, pig
응용분야
immunohistochemistry
western blot
Anti-RNASEH2A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Monoclonal Anti-RNASEH2A antibody produced in mouse, clone 3G5-F5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human RNASEH2A,
human
MISSION® esiRNA, targeting mouse Rnaseh2a,
mouse