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Merck

PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

동의어:
Ki, PA28-gamma, PA28G, PA28gamma, REG-GAMMA
:
UniProtKB ID:
Clone ID:
  • Human(10197) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
  • Mouse(19192) proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
  • Rat(287716) proteasome (prosome, macropain) activator subunit 3
  • Zebrafish(30649) proteasome activator subunit 3
  • domestic cat(101101426) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • dog(480512) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • chicken(420017) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • cow(100336105) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • sheep(101106185) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • naked mole-rat(101710384) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • domestic guinea pig(100721509) proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PSME3 (AB1) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
응용분야
immunohistochemistry
western blot
Anti-PSME3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-PSME3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-PSME3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human, mouse, rat
응용분야
ELISA
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Psme3,
mouse
MISSION® esiRNA, targeting human PSME3,
human