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Merck

NQO1

NAD(P)H dehydrogenase, quinone 1

동의어:
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
:
UniProtKB ID:
Clone ID:
  • Human(1728) Summary: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18104) NAD(P)H dehydrogenase, quinone 1
  • Rat(24314) NAD(P)H dehydrogenase, quinone 1
  • sheep(101121876) NAD(P)H dehydrogenase, quinone 1
  • naked mole-rat(101711262) NAD(P)H dehydrogenase, quinone 1
  • domestic guinea pig(100135582) NAD(P)H dehydrogenase, quinone 1
  • Zebrafish(322506) NAD(P)H dehydrogenase, quinone 1
  • dog(610935) NAD(P)H dehydrogenase, quinone 1
  • domestic cat(101097859) NAD(P)H dehydrogenase, quinone 1
  • cow(519632) NAD(P)H dehydrogenase, quinone 1
  • chicken(769737) NAD(P)H dehydrogenase, quinone 1

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ELISA

Product Number
설명
Human NQO-1 ELISA, for serum, plasma and cell culture supernatants,
human

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-NQO1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-NQO1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
western blot
Anti-NQO1 Rabbit pAb, liquid, Calbiochem®,
종별 반응성
human, mouse
응용분야
Anti-NQO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-NQO1 Antibody, clone 1D12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
설명
Menadione (K3), analytical standard,
human
Menadione, crystalline,
human
Menadione, meets USP testing specifications,
human

Proteins

Product Number
설명
NQO1 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
human
DT Diaphorase (NQO1) human, lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting mouse Nqo1,
mouse
MISSION® esiRNA, targeting human NQO1,
human