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Merck

KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

동의어:
CD309, FLK1, VEGFR, VEGFR2
종:
UniProtKB ID:
Clone ID:
  • Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
  • Mouse(16542) kinase insert domain protein receptor
  • Rat(25589) kinase insert domain receptor
  • Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • sheep(443087) vascular endothelial growth factor receptor-2
  • Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Thale Cress(839585) basic helix-loop-helix protein KIDARI

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ELISA

제품 번호
설명
Mouse Kdr / Vascular Endothelial Growth Factor Receptor 2 ELISA Kit, ,
mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11, clone CH-11, Upstate®, from mouse,
종별 반응성
human, mouse
응용분야
ELISA
immunocytochemistry

western blot
Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody, Upstate®, from rabbit,
종별 반응성
danio, bovine, chicken, horse, human, mouse, primate, rat, zebrafish
응용분야
western blot
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1054) Antibody, clone D1W, rabbit monoclonal, culture supernatant, clone D1W, Upstate®,
종별 반응성
human, mouse
응용분야
western blot
Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR)−Biotin Conjugate antibody, Mouse monoclonal, clone 260.4, KDR-2, purified from hybridoma cell culture,
종별 반응성
human
응용분야
western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
human
SU 5416, ≥98% (HPLC),
human, mouse
Sunitinib malate, ≥98% (HPLC),
human
Pazopanib, ,
human
α-Sexithiophene, ,
human, rat

Proteins

제품 번호
설명
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.
,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human KDR,
human
MISSION® esiRNA, targeting mouse Kdr,
mouse