GRM1
glutamate receptor, metabotropic 1
동의어:
GPRC1A, MGLU1, MGLUR1, SCAR13
종:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Domestic Rabbit GRM1 (100356201), Zebrafish grm1 (100150246), dog GRM1 (484024), domestic cat GRM1 (101094104), cow GRM1 (540485) ...더
UniProtKB ID:
Clone ID:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-Metabotropic Glutamate Receptor 1 Antibody, Chemicon®, from rabbit,
종별 반응성
human
응용분야
immunohistochemistry
Monoclonal Anti-Glutamate antibody produced in mouse, clone GLU-4, ascites fluid,
종별 반응성
wide range
응용분야
ELISA
Anti-GRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Monoclonal Anti-GRM1 antibody produced in mouse, clone 1F7, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
western blot
Small Molecule - Inhibitor
제품 번호
설명
종
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
종
rat, human
Small Molecule - Mixed Agonist/Antagonist
제품 번호
설명
종
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
종
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
종
rat, human