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Merck

GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(2557) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
  • Mouse(14397) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
  • Rat(140675) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • domestic guinea pig(100721252) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • naked mole-rat(101718327) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • sheep(101121776) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • Domestic Rabbit(100339882) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • chicken(422770) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • dog(482132) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • cow(282238) gamma-aminobutyric acid (GABA) A receptor, alpha 4
  • domestic cat(101098052) gamma-aminobutyric acid (GABA) A receptor, alpha 4

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Small Molecule - Agonist

제품 번호
설명
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
human
Isoguvacine hydrochloride, solid,
human
Piperidine-4-sulfonic acid, ,
human
γ-Aminobutyric acid, ≥99%,
human, rat

Small Molecule - Allosteric Modulator

제품 번호
설명
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
human
trans-Dehydroandrosterone, ≥99%,
human, rat
Etomidate, >98% (HPLC), powder,
human
Etomidate, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Antagonist

제품 번호
설명
Picrotoxin, powder,
human
Pregnenolone sulfate sodium salt, ,
human
SR-95531, ≥98% (HPLC), powder,
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
human
trans-Dehydroandrosterone, ≥99%,
human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-GABRA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, human
응용분야
ELISA
immunohistochemistry

western blot
Monoclonal Anti-GABA A Receptor-FITC antibody produced in mouse, clone S398A-34,
종별 반응성
human, mouse
응용분야
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S398A-34,
종별 반응성
human, mouse
응용분야
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S398A-34,
종별 반응성
human, mouse
응용분야
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S398A-34,
종별 반응성
human, mouse
응용분야
immunofluorescence
western blot

Small Molecule - Inhibitor

제품 번호
설명
NO-711 hydrochloride, ≥98% (HPLC),
human
(±)-Vigabatrin, ,
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
human

Small Molecule - Ligand

제품 번호
설명
Etomidate, >98% (HPLC), powder,
human
Flumazenil, >99% (HPLC), solid,
rat, human
Carbamazepine, powder,
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Gabra4,
mouse
MISSION® esiRNA, targeting human GABRA4,
human