DNASE1
deoxyribonuclease I
동의어:
DNL1, DRNI
종:
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), Zebrafish dnase1 (436947), dog DNASE1 (403413), domestic cat DNASE1 (101096195), cow DNASE1 (282217), Horse DNASE1 (100034219), chicken DNASE1 (395725), sheep DNASE1 (101122154) ...더
UniProtKB ID:
Clone ID:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
종별 반응성
bovine, human, rat
응용분야
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, human, rat
응용분야
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
종별 반응성
bovine, human, rat
응용분야
Proteins
제품 번호
설명
종
Deoxyribonuclease I bovine, recombinant, expressed in Pichia pastoris, buffered aqueous glycerol solution, ≥5,000 units/mg protein,
종
Deoxyribonuclease I bovine, recombinant, expressed in Pichia pastoris, lyophilized powder, RNAse and protease, free,
종
Deoxyribonuclease I from bovine pancreas, lyophilized powder, Protein ≥85 %, ≥400 Kunitz units/mg protein,
종
Deoxyribonuclease I from bovine pancreas, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
종