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Merck

CTSB

cathepsin B

동의어:
APPS, CPSB
:
UniProtKB ID:
Clone ID:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • chicken(396329) cathepsin B
  • dog(486077) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • Horse(100060963) cathepsin B
  • sheep(780470) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • domestic guinea pig(100714169) cathepsin B

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Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-Cathepsin B antibody, Mouse monoclonal, clone CB59-4B11, purified from hybridoma cell culture,
종별 반응성
human, rat
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
설명
Calpain Inhibitor I, ≥97% (TLC), powder,
human
Diethylcyanamide, 99%,
human
MG-132(R), ≥95% (HPLC),
human
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
human

Proteins

Product Number
설명
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
human
Cathepsin B from bovine spleen, lyophilized powder, ≥10 units/mg protein,
cow
Cathepsin B Active human, recombinant, expressed in FreeStyle 293-F cells, ≥90% (SDS-PAGE),
human
Cathepsin B from human placenta, lyophilized powder, ≥5 units/mg protein,
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human CTSB,
human
MISSION® esiRNA, targeting mouse Ctsb,
mouse

Small Molecule - Substrate

Product Number
설명
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride, ,
mouse, human, rat