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Merck

CCNH

cyclin H

동의어:
CAK, p34, p37
:
UniProtKB ID:
Clone ID:
  • Human(902) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
  • Mouse(66671) cyclin H
  • Rat(84389) cyclin H
  • domestic guinea pig(100726162) cyclin H
  • naked mole-rat(101714118) cyclin H
  • sheep(101104905) cyclin H
  • Zebrafish(541325) cyclin H
  • cow(615512) cyclin H
  • Horse(100065185) cyclin H
  • domestic cat(101095398) cyclin H
  • dog(479156) cyclin H
  • chicken(427328) cyclin H

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CCNH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-Cyclin H Antibody, clone 3N5S3, Rabbit Monoclonal, ,
종별 반응성
mouse
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-CCNH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-phospho-Cyclin H (pThr315) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot

Proteins

제품 번호
설명
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CCNH,
human
MISSION® esiRNA, targeting mouse Ccnh,
mouse