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Merck

ADRA2C

adrenoceptor alpha 2C

동의어:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
:
UniProtKB ID:
Clone ID:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • cow(407139) alpha-2C adrenergic receptor
  • cow(101902575) adrenoceptor alpha 2C
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C

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Small Molecule - Agonist

제품 번호
설명
Methyldopa for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Methyldopa, British Pharmacopoeia (BP) Reference Standard,
human
Guanfacine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Guanfacine hydrochloride, ≥98% (HPLC),
human

Small Molecule - Antagonist

제품 번호
설명
RX 821002 hydrochloride, solid, ≥98% (HPLC),
human
Yohimbine hydrochloride, ≥98% (HPLC), powder,
human
Idazoxan hydrochloride, ,
human
UK 14,304, ,
human
Mirtazapine, United States Pharmacopeia (USP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Percp antibody produced in mouse, clone S330A-80, purified immunoglobulin,
종별 반응성
human, mouse
응용분야
immunocytochemistry
western blot
Anti-ADRA2C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Rpe antibody produced in mouse, clone S330A-80, purified immunoglobulin,
종별 반응성
human, mouse
응용분야
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Fitc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
종별 반응성
human, mouse
응용분야
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Hrp antibody produced in mouse, clone S330A-80, purified immunoglobulin,
종별 반응성
human, mouse
응용분야
immunocytochemistry
western blot

Small Molecule - Blocker

제품 번호
설명
Agmatine sulfate salt, ≥97%, powder,
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
UK 14,304, ,
human
(−)-Norepinephrine, ≥98%, crystalline,
human, rat
Haloperidol, powder,
human, rat
Clozapine, ,
human, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Adra2c,
mouse