SML0100

GYY4137 Dichloromethane complex

≥98% (HPLC), powder, H₂S donor

• Synonym(s): P-(4-Methoxyphenyl)-P-4-morpholinyl-phosphinodithioic acid, compound with morpholine (1:1), morpholin-4-ium 4-methoxyphenyl(morpholino) phosphinodithioate dichloromethane complex
• Empirical Formula (Hill Notation): C₁₁H₁₆NO₂PS₂ · C₄H₉NO · xCH₂Cl₂
• CAS Number: 106740-09-4
• Molecular Weight: 376.47
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825158
• NACRES: NA.25

Properties

• Product Name: GYY4137 Dichloromethane complex, ≥98% (HPLC)
• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥3 mg/mL
• storage temp.: 2-8°C
• SMILES string: ClCCl.S=P(N1CCOCC1)([S-])C2=CC=C(OC)C=C2.C3COCC[NH2+]3
• InChI: 1S/C11H16NO2PS2.C4H9NO.CH2Cl2/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1;2-1-3/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2;1H2
• InChI key: PKLNNEJKTAMITC-UHFFFAOYSA-N

Description

Application

GYY4137 Dichloromethane complex has been used as a non-isothiocyanate H2S (hydrogen sulfide) donor.

Biochem/physiol Actions

GYY4137 is a small molecule releaser of H₂S with vasodilator and antihypertensive activity. H₂S has been found to be an important biological mediator with multiple effects on neuromodulation, hypertension, inflammation, and vascular tone. GYY4137 should prove useful in the study of the many and varied biological effects of H₂S.

Small molecule releaser of H2S

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable