SMB01064

Dimethylfraxetin

≥90% (LC/MS-ELSD)

• Synonym(s): 6,7,8,-trimethoxycoumarin, 6,7,8-trimethoxychromen-2-one, Fraxidin Methyl Ether
• Empirical Formula (Hill Notation): C₁₂H₁₂O₅
• CAS Number: 6035-49-0
• Molecular Weight: 236.22
• MDL number: MFCD00145039
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• biological source: plant
• Assay: ≥90% (LC/MS-ELSD)
• form: solid
• mol wt: 236.22
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• InChI: 1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3
• InChI key: RAYQKHLZHPFYEJ-UHFFFAOYSA-N

Description

General description

Dimethylfraxetin, also known as 6,7,8-Trimethoxycoumarin, a coumarin derivative, is a natural product commonly found in Pittosporum illicioides, Garcinia multiflora, and Cryptocarya bracteolata. It exhibits a range of biological activities, including anti-inflammatory, antioxidant, anticancer, and antimicrobial properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Biochem/physiol Actions

• Binds to the CB2 receptor and induces immunomodulatory effects.
• Exhibits anti-inflammatory properties by inhibiting prostaglandin synthesis in the human erythroleukemia cell line K562.
• Inhibits the replication of both DNA and RNA.
• Blocks aminoacyl-tRNA binding to ribosomes, inhibiting protein synthesis.
• Binds to phenolic acid receptors on cultured cells.

Features and Benefits

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable