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Key Documents

SAB5702496

Sigma-Aldrich

Anti-SAMHD1 Antibody, clone 4C7B3, Rabbit Monoclonal

Synonym(s):

CHBL2, DCIP, HDDC1, MOP-5, SBBI88

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

4C7B3, monoclonal

form

liquid

mol wt

72 kDa

species reactivity

human

concentration

0.33 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

NRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWNDSTSVQNPTRLREASKSRVQLFKDDPM

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SAMHD1(25939)

General description

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 527-626 of human SAMHD1 (Q9Y3Z3).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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