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SAB3700768

Sigma-Aldrich

Anti-Monkey IgG (γ-chain specific)-Biotin antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

conjugate

biotin conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

monkey

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chain and two light chains connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin.

Specificity

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Monkey IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Goat Serum, Monkey IgG and Monkey Serum. No reaction was observed against Monkey IgA or Monkey IgM.

Immunogen

Monkey IgG gamma heavy chain

Biochem/physiol Actions

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. Macaques (rhesus monkeys) and cynomolgus monkeys (cynos) serves as hosts in synthesizing vaccine, transplantation research, studies of viral diseases, pharmacodynamics and pharmacokinetic and safety assessments of therapeutic candidate Abs (antibodies).

Physical properties

Antibody format: IgG

Physical form

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Reconstitution

Reconstitute with 1.0 mL deionized water (or equivalent).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2

Supplementary Hazards

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Molecular and functional characterization of cynomolgus monkey IgG subclasses.
Jacobsen FW, et al.
Journal of Immunology, 1001685-1001685 (2010)
Molecular Genetics of Immunoglobulin, 244-244 (1987)
The Immunoglobulins: Structure and Function, 269-269 (1998)
Guidenn Sulbaran et al.
Cell reports. Medicine, 3(2), 100528-100528 (2022-03-03)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like particles. Soluble S glycoprotein trimer stabilization by
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)

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