H7750

DL-Histidine

≥99% (TLC), suitable for ligand binding assays

• Synonym(s): (±)-2-Amino-3-(4-imidazolyl)propionic acid
• Empirical Formula (Hill Notation): C₆H₉N₃O₂
• CAS Number: 4998-57-6
• Molecular Weight: 155.15
• Beilstein: 7800
• EC Number: 225-660-9
• MDL number: MFCD00005208
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895803
• NACRES: NA.26

Properties

• product name: DL-Histidine, ≥99% (TLC)
• Assay: ≥99% (TLC)
• form: powder
• technique(s): ligand binding assay: suitable
• mp: 273 °C (dec.) (lit.)
• solubility: 0.5 M HCl: soluble
• application(s): peptide synthesis
• SMILES string: NC(Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)
• InChI key: HNDVDQJCIGZPNO-UHFFFAOYSA-N

Description

Application

DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).

DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves