AV48140

Anti-PGK1 (AB1) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-MGC117307, Anti-MGC142128, Anti-MGC8947, Anti-MIG10, Anti-PGKA, Anti-Phosphoglycerate kinase 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 44 kDa
• species reactivity: horse, sheep, bovine, rat, human, guinea pig, dog, mouse, rabbit
• concentration: 0.5 mg - 1 mg/mL
• technique(s): western blot: suitable
• NCBI accession no.: NP_000282
• UniProt accession no.: P00558
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PGK1(5230)

Description

General description

Phosphoglycerate kinase 1 (PGK1) is an enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate during glycolysis. PGK1 expression has been correlated to CXCR4 expression, survival and bone marrow metastasis in neuroblastoma patients.
Rabbit Anti-PGK1 antibody recognizes bovine, human, mouse, rat, and canine PGK1.

Immunogen

Synthetic peptide directed towards the N terminal region of human PGK1

Application

Rabbit Anti-PGK1 antibody has been used as a loading control in immunoblotting assays. The product is suitable at a concentration of 0.5μg/ml for western blots.

Biochem/physiol Actions

PGK1 is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The protein may also act as a cofactor for polymerase alpha.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Sequence

Synthetic peptide located within the following region: PEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable