PHR2033

Rivastigmine Related Compound E

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): (S)-1-(3-{[Ethyl(methyl)carbamoyl]oxy}phenyl)-N,N,N-trimethylethanaminium iodide
• Empirical Formula (Hill Notation): C₁₅H₂₅IN₂O₂
• Molecular Weight: 392.28
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1604950
• API family: rivastigmine
• CofA: current certificate can be downloaded
• packaging: pkg of 30 mg
• application(s): pharmaceutical
• format: neat
• storage temp.: -10 to -25°C

Description

General description

Rivastigmine Related Compound E is an impurity of rivastigmine, a novel acetylcholine esterase inhibitor. It is mainly used for the treatment of Alzheimer′s disease.

Application

Rivastigmine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using electroanalytical technique and high-performance thin layer chromatography method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB4763 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330
• Precautionary Statements: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable