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P6474

Sigma-Aldrich

TWEEN® 80

viscous liquid, Preservative Free, Low-peroxide; Low-carbonyls

Synonym(s):

Tween® 80KR, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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About This Item

CAS Number:
9005-65-6
MDL number:
MFCD00082107
UNSPSC Code:
12161900
NACRES:
NA.21

Quality Level

300

description

non-ionic

form

viscous liquid

mol wt

micellar avg mol wt 79,000
average mol wt 1310

composition

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

impurities

≤0.5 μmol/g Peroxides
≤1.0 μmol/g Carbonyls
≤3.0% water

CMC

0.012 mM (20-25°C)

transition temp

cloud point 65 °C

density

1.06 g/mL at 25 °C

HLB

15

storage temp.

−20°C

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM1268
SLBR5167V
SLBR4164V
SLBF8247V
SLBF5908V

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Martin L Cross et al.
Clinical and vaccine immunology : CVI, 16(9), 1378-1380 (2009-07-03)
Cultures of Mycobacterium bovis BCG, comprising predominantly single-cell bacilli, were prepared in broth without animal-derived reagents. When formulated into a vegetable-derived lipid matrix, the vaccine was stable in vitro and was immunogenic in vivo upon feeding it to mice. This
Deepak Almeida et al.
Antimicrobial agents and chemotherapy, 53(10), 4178-4184 (2009-07-22)
To investigate the antagonism between isoniazid (INH) and rifampin (rifampicin) (RIF)-pyrazinamide (PZA) combination observed in Mycobacterium tuberculosis-infected mice, extensive pharmacokinetic studies of INH were performed and followed by experiments to assess the impact of increasing doses of INH on the
Hau-Ren Chen et al.
International journal of molecular sciences, 12(11), 8245-8258 (2011-12-17)
The separation of mercury ions from artificially contaminated water by the foam fractionation process using a biosurfactant (surfactin) and chemical surfactants (SDS and Tween-80) was investigated in this study. Parameters such as surfactant and mercury concentration, pH, foam volume, and
Syed A Sattar et al.
PloS one, 6(2), e17340-e17340 (2011-03-11)
Human noroviruses (HuNoV), a major cause of acute gastroenteritis worldwide, cannot be readily cultured in the lab. Therefore, a feline calicivirus (FCV) is often used as its surrogate to, among other things, test alcohol-based handrubs (ABHR). The more recent laboratory
Qun Wang et al.
Brain research, 1285, 188-195 (2009-06-17)
The group IIA secretory phospholipase A2 (sPLA(2)-IIA) has been studied extensively because of its involvement in inflammatory processes. Up-regulation of this enzyme has been shown in a number of neurodegenerative diseases including cerebral ischemia and Alzheimer's disease. PX-18 is a
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