Skip to Content
Merck
All Photos(1)

Key Documents

07-204

Sigma-Aldrich

Anti-Sec61α Antibody

serum, Upstate®

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

canine, rat, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_013336
NM_018144

UniProt accession no.

P61619

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SEC61A1(29927)

Specificity

Sec61α

Immunogen

peptide conjugated to KLH and to BSA, corresponding to amino acids 463-476 of human Sec61a (C-KEQSEVGSMGALLF)

Application

Detect Sec61α using this Anti-Sec61α Antibody validated for use in IP & WB.
Research Category
Metabolism
Research Sub Category
Ion & Transport Channels

Quality

routinely evaluated by immunoblot on a rat brain microsomal preparation

Target description

40kDa

Physical form

Antiserum
antiserum containing 0.05% sodium azide and 30% glycerol

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

W Mothes et al.
The EMBO journal, 13(17), 3973-3982 (1994-09-01)
We have extended a previously developed photo-crosslinking approach to systematically probe the protein environment of the secretory protein preprolactin, trapped during its transfer through the endoplasmic reticulum membrane. Single photoreactive groups were placed at various positions of nascent polypeptide chains
Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface.
Caroline Delandre,Taryn R Penabaz,A Lorena Passarelli,Stephen K Chapes,Rollie J Clem
Experimental Cell Research null
D Görlich et al.
Cell, 71(3), 489-503 (1992-10-30)
SEC61p is essential for protein translocation across the endoplasmic reticulum membrane of S. cerevisiae. We have found a mammalian homolog that shows more than 50% sequence identity with the yeast protein. Moreover, several regions of SEC61p have significant similarities with
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane.
Jungnickel, B and Rapoport, T A
Cell, 82, 261-270 (1995)
Hydrophobic and basic domains target proteins to lipid droplets.
Ingelmo-Torres, M; Gonzalez-Moreno, E; Kassan, A; Hanzal-Bayer, M; Tebar, F; Herms et al.
Traffic null
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service