M-009

(±)-Methamphetamine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₀H₁₅N
• CAS Number: 7632-10-2
• Molecular Weight: 149.23
• MDL number: MFCD00079115
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: CC(NC)CC1=CC=CC=C1
• InChI: 1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
• InChI key: MYWUZJCMWCOHBA-UHFFFAOYSA-N

Description

General description

Methamphetamine is a psychostimulant drug of the phenethylamine and amphetamine classes known by the street names "meth," "ice," and "glass". This Snap-N-Spike^® reference solution is applicable for use in LC/MS or GC/MS applications such as clinical toxicology, sports testing, forensic analysis, or urine drug testing. The dextrorotatory isomer of methamphetamine is a pharmaceutical drug sold under the trade name Desoxyn^® for treatment of ADHD and obesity.

Application

• Modeling methamphetamine use disorder and relapse in animals: short- and long-term epigenetic, transcriptional, and biochemical consequences in the rat brain: This research explores the utility of (±)-Methamphetamine in neurochemical studies, specifically examining its epigenetic, transcriptional, and biochemical impacts on the rat brain over short and long periods. The study underscores the importance of methamphetamine as a research chemical in understanding addiction and relapse mechanisms (Elhadi K, et al., 2023).


• Vaccines as Immunotherapies for Substance Use Disorders: This review highlights innovative approaches using (±)-Methamphetamine in the development of vaccines aimed at treating substance use disorders. It exemplifies cutting-edge pharmaceutical applications in creating immunotherapies to combat addiction (Kosten TR, 2024).


• The reflections of health service providers on implementing contingency management for methamphetamine use disorder in Australia: This article discusses the practical applications of (±)-Methamphetamine in contingency management strategies for treating methamphetamine use disorders, reflecting on real-world challenges and solutions from healthcare providers (Clay S, et al., 2024).


• Correction: PrEP Uptake and Methamphetamine Use Patterns in a 4-Year U.S. National Prospective Cohort Study of Sexual and Gender Minority People, 2017-2022: This correction notice relates to a study that investigates patterns of methamphetamine use and its implications in public health, especially in preventive medicine strategies among sexual and gender minority groups (Guo Y, et al., 2024).


• Identification of the circRNA-miRNA-mRNA network for treating methamphetamine-induced relapse and behavioral sensitization with cannabidiol: This research demonstrates the use of (±)-Methamphetamine to explore the genomic and molecular pathways involved in drug addiction and relapse, offering insights into potential treatments using cannabidiol (Liu L, et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Desoxyn is a registered trademark of Abbott Laboratories Corp.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H301 + H311 + H331 - H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup