Skip to Content
Merck
All Photos(1)

Documents

860655P

Avanti

sphinganine-1-phosphate (d17:0)

Avanti Research™ - A Croda Brand 860655P, powder

Synonym(s):

D-erythro-sphinganine-1-phosphate (C17 base)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H38NO5P
CAS Number:
474923-29-0
Molecular Weight:
367.46
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860655P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860655P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C17H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h16-17,19H,2-15,18H2,1H3,(H2,20,21,22)/t16-,17+/m0/s1

InChI key

RTCZJPCPBSBOKB-DLBZAZTESA-N

Application

Sphinganine-1-phosphate (d17:0) has been used as an internal standard in mass spectroscopy for quantification of shingolipids.

Biochem/physiol Actions

Exogenous sphinganine 1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1) and exhibits protective effects against hepatic and renal ischemia and reperfusion (IR).

Packaging

5 mL Amber Glass Screw Cap Vial (860655P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P 1 receptor activation
Park SW, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 90(8), 1209-1209 (2010)
TP53 is required for BECN1-and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition
Lim S, et al.
Autophagy, 14(6), 942-957 (2018)
Ladan Dawoody Nejad et al.
Scientific reports, 10(1), 8268-8268 (2020-05-20)
Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service