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850385P

Avanti

18:2 (Cis) PC (DLPC)

Avanti Research - A Croda Brand

Synonym(s):

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(18:2(9Z,12Z)/18:2(9Z,12Z))

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About This Item

Empirical Formula (Hill Notation):
C44H80NO8P
CAS Number:
Molecular Weight:
782.08
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dilinoleoyl-sn-glycero-3-phosphocholine

Assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850385P-200mg)
pkg of 1 × 25 mg (850385P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O

InChI

1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1

InChI key

FVXDQWZBHIXIEJ-LNDKUQBDSA-N

General description

18:2 (Cis) PC (DLPC) is a synthetic phosphatidylcholine.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:2 (Cis) PC (DLPC) has been used for liposome preparation.

Packaging

5 mL Clear Glass Sealed Ampule (850385P-200mg)
5 mL Clear Glass Sealed Ampule (850385P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yueheng Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 33(11), 2780-2789 (2017-03-02)
We report the ability of hydrophobically modified polypeptoids (HMPs), which are amphiphilic pseudopeptidic macromolecules, to connect across lipid bilayers and thus form layered structures on liposomes. The HMPs are obtained by attaching hydrophobic decyl groups at random points along the
Force-from-lipids gating of mechanosensitive channels modulated by PUFAs
Ridone P, et al.
Journal of the Mechanical Behavior of Biomedical Materials, 79, 158-167 (2018)
Xiao Wu et al.
International journal of pharmaceutics, 579, 119168-119168 (2020-02-23)
Beta-lapachone (β-Lap) is an anticancer drug activated by the NAD(P)H:quinone oxidoreductase (NQO1), an enzyme over-expressed in a large variety of tumors. B-Lap is poorly soluble in water and in most biocompatible solvents. Micellar systems, liposomes and cyclodextrins (CDs) have been
Mariana Vignoni et al.
Langmuir : the ACS journal of surfaces and colloids, 34(50), 15578-15586 (2018-11-21)
Pterins are natural products that can photosensitize the oxidation of DNA, proteins, and phospholipids. Recently, a new series of decyl-chain (i.e., lipophilic) pterins were synthesized and their photophysical properties were investigated. These decyl-pterins led to efficient intercalation in large unilamellar
Samuel C R Sherratt et al.
Biochimica et biophysica acta. Biomembranes, 1862(7), 183254-183254 (2020-03-07)
Oxidation of small dense low-density lipoprotein (sdLDL) and membranes is causally related to atherosclerosis. The omega-3 fatty acid (FA) eicosapentaenoic acid (EPA, 20:5, ω-3) significantly reduced oxidized LDL in patients with hypertriglyceridemia by unknown mechanisms. We compared EPA effects to

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