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Key Documents

ALD00629

Sigma-Aldrich

6-(1-Cyclohexyl-1-(5-methylpyridin-2-yl)ethyl)pyridin-2(1H)-one

≥95%

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About This Item

Empirical Formula (Hill Notation):
C19H24N2O
CAS Number:
Molecular Weight:
296.41
UNSPSC Code:
12352100
NACRES:
NA.21

Quality Level

Assay

≥95%

form

powder or chunks

mp

146-149 °C

storage temp.

−20°C

SMILES string

O=C1C=CC=C(N1)C(C2=NC=C(C=C2)C)(C)C3CCCCC3

Application

This ligand was developed by the Yu lab to enable the Pd-catalyzed dehydrogenation of aliphatic carboxylic acids through a typically challenging activation of the β-methylene C-H bond. This method is chemoselective to carboxylic acids even in the presence of other enolizable functional groups, and may also viably utilize molecular oxygen as the terminal oxidant for the transformation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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