A70704

(1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

99%

• Synonym(s): D-(−)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
• Linear Formula: HOCH₂CH(NH₂)CH(C₆H₄NO₂)OH
• CAS Number: 716-61-0
• Molecular Weight: 212.20
• EC Number: 211-938-7
• MDL number: MFCD00078126
• UNSPSC Code: 12352116
• PubChem Substance ID: 24891170
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99%
• form: powder
• optical activity: [α]25/D −30°, c = 1 in 6 M HCl
• mp: 163-165 °C (lit.)
• SMILES string: N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C9H12N2O4/c10-8(5-12)9(13)6-1-3-7(4-2-6)11(14)15/h1-4,8-9,12-13H,5,10H2/t8-,9-/m1/s1
• InChI key: OCYJXSUPZMNXEN-RKDXNWHRSA-N

Description

Application

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves