911569
Polyester bis-MPA dendron
no. Surface Groups 4, NHBoc, 1 Biotin (core), generation 2
Synonym(s):
Biotin-NHBoc dendron, Bis-MPA dendron
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About This Item
Empirical Formula (Hill Notation):
C65H108N6O28S
Molecular Weight:
1453.64
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
form
solid (Viscous)
mol wt
generation 2
no. Surface Groups
4
color
colorless to white
storage temp.
−20°C
General description
- Polymer architecture: Dendron
- Generation: 2
- Core functional group: Biotin
- End Group Functionality: NHBoc
- No. Surface Groups: 4
- Calculated Mol. Wt.: 1453.7 g/mol
- bis-MPA = 2,2-bis(hydroxymethyl)propionic acid
Application
Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications.The NHBoc-functionalized corona and Biotin-functionalized core of this product can be readily used in bioconjugation reactions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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