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901701

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) diacrylate

average Mn ~12,500

Synonym(s):

PEG-PPG-PEG, Poloxamer F127 diacrylate

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About This Item

Linear Formula:
C3H3O[C2H4O]x[C3H6O]y[C2H4O]zC3H3O2
UNSPSC Code:
51171641
NACRES:
NA.23

form

powder

mol wt

average Mn ~12,500

color

white to faint yellow

storage temp.

−20°C

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Application

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) diacrylate (PEG-PPG-PEG) is a bifunctional acrylate-based amphiphilic triblock copolymer, which can be used in applications such as pharmaceutics, biomedical and personal care products. It can also be used in the synthesis of alternating block polyurethanes, which can be potentially used in drug delivery.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCH3087

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Synthesis, characterizations and biocompatibility of alternating block polyurethanes based on P3/4HB and PPG-PEG-PPG
Li G, et al.
Journal of Biomedical Materials Research Part A, 98(1), 88-99 (2011)
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization
Di Biase M, et al.
Soft Matter, 7(10), 4928-4937 (2011)
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Manuela, D. B et al.
Soft Matter, 7, 4928-4937 (2011)
J J Escobar-Chávez et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 9(3), 339-358 (2007-01-09)
It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an
Self-Assembly of Pluronic F127 Diacrylate in Ethylammonium Nitrate: Structure, Rheology, and Ionic Conductivity before and after Photo-Cross-Linking.
Lopez Barron C R, et al.
Macromolecules, 49(14), 5179-5189 (2016)
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