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Sigma-Aldrich

N-Boc- 2,2′-(ethylenedioxy)diethylamine

≥95.0% (NT), for peptide synthesis

Synonym(s):

N-Boc-3,6-dioxa-1,8-octanediamine, tert-Butyl 2-[2-(2-aminoethoxy)ethoxy]ethylcarbamate

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About This Item

Empirical Formula (Hill Notation):
C11H24N2O4
CAS Number:
Molecular Weight:
248.32
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

product name

N-Boc- 2,2′-(ethylenedioxy)diethylamine, ≥95.0% (NT)

Assay

≥95.0% (NT)

form

liquid

reaction suitability

reagent type: cross-linking reagent

density

1.046 g/mL at 20 °C

functional group

Boc
amine

SMILES string

NCCOCCOCCNC(OC(C)(C)C)=O

InChI

1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)

InChI key

OCUICOFGFQENAS-UHFFFAOYSA-N

Application

Linker reagent for the prep. of a broad variety of linked tags, monomers for polymerisation, ionophores etc., e.g. biotinylation reagents.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Sigal, G. B., et al.
Journal of the American Chemical Society, 118, 3789-3800 (1996)
Spinke, J., et al.
The Journal of Physical Chemistry, 99(9), 7012-7019 (1993)
Michelle Trester-Zedlitz et al.
Journal of the American Chemical Society, 125(9), 2416-2425 (2003-02-27)
A method is described for the elucidation of protein-protein interactions using novel cross-linking reagents and mass spectrometry. The method incorporates (1) a modular solid-phase synthetic strategy for generating the cross-linking reagents, (2) enrichment and digestion of cross-linked proteins using microconcentrators
Braun, M., et al.
European Journal of Organic Chemistry, 7, 1173 - 1182 (2000)

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