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578045

Sigma-Aldrich

4-Morpholinopiperidine

98%

Synonym(s):

4-(4-Piperidinyl) morpholine

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About This Item

Empirical Formula (Hill Notation):
C9H18N2O
CAS Number:
53617-35-9
Molecular Weight:
170.25
MDL number:
MFCD03274733
UNSPSC Code:
12352100
PubChem Substance ID:
24880906
NACRES:
NA.22

Quality Level

100

Assay

98%

bp

100-115 °C/0.15-0.20 mmHg (lit.)

mp

40-43 °C (lit.)

functional group

ether

SMILES string

C1CC(CCN1)N2CCOCC2

InChI

1S/C9H18N2O/c1-3-10-4-2-9(1)11-5-7-12-8-6-11/h9-10H,1-8H2

InChI key

YYBXNWIRMJXEQJ-UHFFFAOYSA-N

Application

4-Morpholinopiperidine may be used to synthesize 2-(4-morpholinopiperidin-1-yl)-5-nitrobenzonitrile and 9-bromo-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile.
Reactant for synthesis of:
  • Selective adenosine A2A receptor antagonists
  • Antidepressents
  • Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells
  • Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
  • Quinoline derivatives with antimicrobial activity
  • Antimalarials

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBZ0068V
SHBC7389V
SHBC1374V
13896PKV
13896PK

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"Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)"
Kinoshita K, et al.
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"A new phenylpyrazoleanilide, y-320, inhibits interleukin 17 production and ameliorates collagen-induced arthritis in mice and cynomolgus monkeys"
Ushio H, et al.
Pharmaceuticals (Basel, Switzerland), 7(01), 1-17 (2013)

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