480061

2,6-Dimethylphenylboronic acid

≥95.0%

• Synonym(s): 2,6-Dimethylbenzeneboronic acid, 2,6-Xyleneboronic acid, 2,6-Xylylboronic acid
• Linear Formula: (CH₃)₂C₆H₃B(OH)₂
• CAS Number: 100379-00-8
• Molecular Weight: 149.98
• MDL number: MFCD01009693
• UNSPSC Code: 12352103
• PubChem Substance ID: 24871544
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95.0%
• impurities: <10% water
• mp: 105 °C (dec.) (lit.)
• SMILES string: Cc1cccc(C)c1B(O)O
• InChI: 1S/C8H11BO2/c1-6-4-3-5-7(2)8(6)9(10)11/h3-5,10-11H,1-2H3
• InChI key: ZXDTWWZIHJEZOG-UHFFFAOYSA-N

Description

Application

Reagent used for

• Palladium catalyzed Suzuki-Miyaura coupling reactions
• One-pot ipso-nitration of arylboronic acids including broader substrate scope of heterocycles and functional groups
• Nickel-Catalyzed Cross-Coupling of Chromene Acetals and Boronic Acids
• Visible-light initiated aerobic oxidative hydroxylation catalyzed by Ru-complex
• Rhodium(I)-catalyzed 1,4-addition reactions
• Pd-catalyzed homocouplings
• Expanded scope of Cu assisted Suzuki-Miyaura coupling reactions including aryl chlorides and polyhalo aryl boronates

Reagent used in Prepration of

• Orally bioavialable G Protein-Coupled Receptor 40 agonists for diabetes treatment
• Solid phase synthesis and antitumor structure-activity relationship of Smac triazoloprolines and biarylalanines tetrapeptide libraries
• Protein Kinase inhibitors

Other Notes

contains varying amounts of anhydride

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves