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464244

Sigma-Aldrich

Hydroxybutyl methacrylate, mixture of isomers

94%

Synonym(s):

HOB

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About This Item

Empirical Formula (Hill Notation):
C8H14O3
CAS Number:
13159-51-8
Molecular Weight:
158.19
MDL number:
MFCD19707078
UNSPSC Code:
12162002
PubChem Substance ID:
24870154
NACRES:
NA.23

Assay

94%

contains

200 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.45 (lit.)

bp

180 °C (lit.)

density

1.006 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

O=C(OCC(O)CC)C(=C)C

InChI

1S/C8H14O3/c1-4-7(9)5-11-8(10)6(2)3/h7,9H,2,4-5H2,1,3H3

InChI key

IEVADDDOVGMCSI-UHFFFAOYSA-N

Application

  • Supplementary Information for “Permeable Protein-Loaded Polymersome Cascade Nanoreactors by Polymerization-Induced Self-Assembly”: This study involves the use of 2-hydroxypropyl methacrylate, a mixture of isomers, as a precursor in the creation of protein-loaded nanoreactors (LD Blackman et al., 2020).
  • Shape-Shifting Thermoresponsive Block Copolymer Nano-Objects: Explores the use of hydroxybutyl methacrylate (HBMA) in the synthesis of block copolymer nano-objects, focusing on its ability to shift shapes in response to temperature changes (SJ Hunter et al., 2023).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H317,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP1469
MKCM4189
MKCJ5926
MKCF4497
MKCC9303

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Articles

Continuous Flow Manufacturing for Monomer Synthesis

The manufacture of monomers for use in ophthalmic applications is driven by the need for higher purity, improved reliability of manufacturing supply, but ultimately by the need for the increased comfort, convenience, and safety of contact lens wearers. Daily wear contact lenses have the potential to fill this need for many customers; however, their widespread use is constrained by higher costs compared to weekly- or monthly-based lenses. New approaches that improve cost structure and result in higher quality raw materials are needed to help make contact lenses more affordable and accelerate growth of the contact lens market.

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