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Merck

IL6

interleukin 6 (interferon, beta 2)

Synonyms:
BSF2, HGF, HSF, IFNB2, IL-6
Species:
UniProtKB ID:
Gene ID:
  • Human(3569) Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Mouse(16193) interleukin 6
  • Rat(24498) interleukin 6
  • Goat(100860785) interleukin 6 (interferon, beta 2)
  • sheep(443406) interleukin 6 (interferon, beta 2)
  • Domestic Rabbit(100008733) interleukin 6 (interferon, beta 2)
  • naked mole-rat(101702602) interleukin 6 (interferon, beta 2)
  • Zebrafish(100885851) interleukin 6 (interferon, beta 2)
  • domestic cat(493687) interleukin 6 (interferon, beta 2)
  • cow(280826) interleukin 6 (interferon, beta 2)
  • cow(517016) interleukin 6 (interferon, beta 2)
  • Horse(100034196) interleukin 6 (interferon, beta 2)
  • dog(403985) interleukin 6 (interferon, beta 2)
  • chicken(395337) interleukin 6 (interferon, beta 2)

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ELISA

Product Number
Description
Species
Porcine IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
dog
Mouse IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Mouse IL-6 ELISA Kit, for cell and tissue lysates,
Species
rat
Rat IL-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
rat

Small Molecule - Antagonist

Product Number
Description
Species
Probucol, analytical standard,
Species
human
4-Hydroxytamoxifen, analytical standard, (E) and (Z) isomers (50:50),
Species
human, rat
(Z)-4-Hydroxytamoxifen, ≥98% Z isomer,
Species
human, rat
4-Hydroxytamoxifen, ≥70% Z isomer (remainder primarily E-isomer),
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Interleukin-6 Antibody, serum, Chemicon®,
Species Reactivity
sheep
Application
ELISA
western blot
Anti-IL6, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-Interleukin-6 Antibody, clone 4B6, clone 4B6, Chemicon®, from mouse,
Species Reactivity
sheep
Application
ELISA
Anti-Interleukin-6 Antibody, clone B-E8, clone B-E8, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

neutralization
SILuRich Anti-IL6 MAb, biotin conjugated, clone IL6-4G1, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SILuProt IL6 Interleukin 6 human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled,
Species
human
SILuLite IL6 Interleukin 6 human, recombinant, expressed in HEK 293 cells, MS protein standard,
Species
human
Interleukin-6 human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
Species
human
IL-6 from rat, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Species
rat
Interleukin-6 from mouse, IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il6,
Species
mouse
MISSION® esiRNA, targeting human IL6,
Species
human