SML1162

5-Fluoro-1-propargyl-uracil

≥98% (HPLC)

• 別名: 1-Propargyl-5-fluorouracil, 5-Fluoro-1-(2-propyn-1-yl)-2,4(1H,3H)-pyrimidinedione
• 実験式（ヒル表記法）: C₇H₅FN₂O₂
• CAS番号: 69849-33-8
• 分子量: 168.13
• MDL番号: MFCD18364451
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825692
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: H₂O: 1 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: O=C1C(F)=CN(CC#C)C(N1)=O
• InChI: 1S/C7H5FN2O2/c1-2-3-10-4-5(8)6(11)9-7(10)12/h1,4H,3H2,(H,9,11,12)
• InChI Key: GMCOGJQJFDQZCP-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

5-Fluoro-1-propargyl-uracil is a biologically inert precursor, a prodrug that can be bioorthogonally activated to 5-fluorouracil iside a tumor that has a previously implanted palladium catalyst. Preliminary tests with pancreatic and colorectal cancer cells resulted in the death of than 80% of the malignant cells.

特徴および利点

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable