SAB4300270

Anti-phospho-AURKA (pThr²⁸⁸) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗AIK抗体 ウサギ宿主抗体, 抗ARK1抗体 ウサギ宿主抗体, 抗AURA抗体 ウサギ宿主抗体, 抗AURORA2抗体 ウサギ宿主抗体
• MDL番号: MFCD06411780
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: ~48 kDa
• 化学種の反応性: mouse, human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• アイソタイプ: IgG
• 免疫原配列: (R-T-TP-L-M)
• NCBIアクセッション番号: NP_003591.2
• UniProtアクセッション番号: O14965
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr288)
• 遺伝子情報: human ... AURKA(6790)

詳細

免疫原

Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M), according to the protein AURKA.

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

特徴および利点

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ターゲットの説明

Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable