H8909

HBcAg core human

~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli

• 別名: Hepatitis B virus core antigen
• MDL番号: MFCD02264925
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• リコンビナント: expressed in E. coli
• 品質水準: 200
• アッセイ: ≥95% (SDS-PAGE)
• 分子量: 18 kDa
• 濃度: ~1 mg/mL
• UniProtアクセッション番号: G9G988
• 保管温度: −20°C
• 遺伝子情報: hepatitis B virus ... HBVgp4(944568) ; human ... HBVgp4(944568)

詳細

詳細

amino acids 1-183 of HBV core antigen.

生物化学的／生理学的作用

HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.

Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.

物理的形状

Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable