おすすめの製品
由来生物
mouse
品質水準
抗体製品の状態
purified antibody
クローン
monoclonal
化学種の反応性
rat, mouse, human
メーカー／製品名
Neuro-Chrom
テクニック
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
アイソタイプ
IgG1
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
詳細
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology.
特異性
Cat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
免疫原
Epitope: Whole Neuron Marker
アプリケーション
Research Category
ニューロサイエンス
ニューロサイエンス
Research Sub Category
神経細胞及びグリアマーカー
神経細胞及びグリアマーカー
品質
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
物理的形状
Blended monoclonal antibody cocktail in PBS with 0.05% NaN3
Format: Purified
保管および安定性
Maintain at 2-8°C for up to 1 year from date of receipt.
アナリシスノート
Control
Rat E18 cortex primary neurons
Rat E18 cortex primary neurons
法的情報
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB2300:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Harald Lund et al.
Nature immunology, 19(5), 1-7 (2018-04-18)
The cytokine transforming growth factor-β (TGF-β) regulates the development and homeostasis of several tissue-resident macrophage populations, including microglia. TGF-β is not critical for microglia survival but is required for the maintenance of the microglia-specific homeostatic gene signature1,2. Under defined host
Short-term fasting induces profound neuronal autophagy.
Alirezaei, M; Kemball, CC; Flynn, CT; Wood, MR; Whitton, JL; Kiosses, WB
Autophagy null
Erdinç Dursun et al.
PloS one, 12(11), e0188605-e0188605 (2017-11-28)
Our recent study indicated that vitamin D and its receptors are important parts of the amyloid processing pathway in neurons. Yet the role of vitamin D receptor (VDR) in amyloid pathogenesis is complex and all regulations over the production of
Pankaj Patyal et al.
Neurochemical research, 45(3), 663-671 (2019-11-30)
The myelin proteolipid protein gene (PLP1) encodes the most abundant protein in CNS myelin. Expression of the gene must be strictly regulated, as evidenced by human X-linked leukodystrophies resulting from variations in PLP1 copy number, including elevated dosages as well
Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by ?7 nicotinic receptor agonist.
Narla, ST; Klejbor, I; Birkaya, B; Lee, YW; Morys, J; Stachowiak, EK; Prokop et al.
Stem Cells Translational Medicine null
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