8.22336

Thioglycolic acid

for synthesis

• 別名: Thioglycolic acid, Mercaptoacetic acid, 2-Mercaptoethanoic acid
• 実験式（ヒル表記法）: C₂H₄O₂S
• CAS番号: 68-11-1
• 分子量: 92.12
• MDL番号: MFCD00004876
• UNSPSCコード: 12352106
• EC Index Number: 200-677-4
• NACRES: NA.22

特性

• 蒸気圧: 0.1 hPa ( 20 °C)
• 品質水準: 200
• 形状: liquid
• 有効性: 73 mg/kg LD₅₀, oral (Rat)
• pH: 1 (20 °C in H₂O)
• bp: 220 °C/1013 hPa (decomposition)
• mp: -16.5 °C
• 転移温度: flash point 131.5 °C
• 密度: 1.325 g/cm³ at 20 °C
• 保管温度: 2-8°C
• InChI: 1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
• InChI Key: CWERGRDVMFNCDR-UHFFFAOYSA-N

詳細

アプリケーション

• Biocompatible Drug Delivery Films: Thioglycolic acid enhances the film-forming ability and bioadhesiveness of mucilaginous polysaccharides derived from Cassia uniflora seeds. This innovation is pivotal in drug delivery applications, offering controlled release and improved mucosal adhesion properties (Deore et al., 2024).
• Surface Plasmon Resonance in Nanoparticle Research: The interfacial reactivity of gold nanoparticles can be inferred via surface plasmon resonance measurements, with thioglycolic acid playing a crucial role in modifying nanoparticle surfaces to enhance their reactive properties. This is significant for advancements in nanotechnology and material sciences (Romain et al., 2023).
• Enhanced SERS for Virus Detection: Thioglycolic acid contributes to the fabrication of flexible electrospinning nano-fiber membranes that are pivotal in the detection of respiratory tract transmission viruses using Surface Enhanced Raman Scattering (SERS). This application is crucial in improving public health surveillance and response systems (Sun et al., 2024).

アナリシスノート

Assay (iodometric): ≥ 95.0 %
Density (d 20 °C/ 4 °C): 1.325 - 1.335
Identity (IR): passes test
The assay stated on the certificate of analysis refers to the date of examination. A gradual substance-specific content reduction, especially at higher temperatures, must be expected. The average content reduction at the required storage temperature of +2°c to +8°C is about 1% per month.

安全性情報

• ピクトグラム: GHS05,GHS06
• シグナルワード: Danger
• 危険有害性情報: H301 + H311 + H331 - H314 - H317
• 注意書き: P261 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• 引火点(°F): 266.0 °F - closed cup
• 引火点(℃): 130 °C - closed cup