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Merck

PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

別名:
DOD, UBL5
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5300) Summary: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(23988) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • Rat(298696) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Thale Cress(843693) auxin efflux carrier component 1
  • Zebrafish(393721) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • domestic cat(101087904) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • dog(484963) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • chicken(100859153) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • naked mole-rat(101708402) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • domestic guinea pig(100726337) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • cow(535470) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • sheep(101110756) peptidylprolyl cis/trans isomerase, NIMA-interacting 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗PIN1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
Anti-phospho-Pin1 (pSer16) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
western blot
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
Anti-phospho-Pin1 (pSer16) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-Pin1 Antibody, clone 5B4.1, clone 5B4.1, from mouse,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
シクロヘキシミド, from microbial, ≥94% (TLC),
Species
human
シクロヘキシミド 溶液, Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture,
Species
human
シクロヘキシミド, ≥90% (HPLC),
Species
human
シクロヘキシミド, Biotechnology Performance Certified,
Species
human
シクロヘキシミド 溶液, 0.1%, suitable for microbiology,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PIN1,
Species
human
MISSION® esiRNA, targeting mouse Pin1,
Species
mouse